Manchester United manager Ruben Amorim has confirmed that defenders Matthijs de Ligt and Leny Yoro will likely be unavailable for the upcoming Premier League clash against Chelsea on Friday at Stamford Bridge.

Speaking during his pre-match press conference, Amorim expressed uncertainty about the defenders' availability but indicated they would probably not travel with the squad.

"I don't know if they [De Ligt and Yoro] are going to be available," Amorim said. "I think they will not go to Chelsea, but some are a possibility for the final."

De Ligt, who is currently recovering from a knee problem, has already missed Manchester United's previous two fixtures. Meanwhile, Yoro sustained a knock during the Red Devils' 2-0 defeat to West Ham United last weekend.

The defensive absences come at a critical time for Manchester United, who currently sit in 16th position in the Premier League table, while their opponents Chelsea occupy 5th place.

Amorim's reference to "the final" suggests he may be prioritizing player recovery for an upcoming cup competition, though specific details were not provided in his statement.

The match at Stamford Bridge represents an important fixture for both clubs as the Premier League season progresses, with Chelsea pushing for Champions League qualification while Manchester United look to climb away from the lower half of the table.